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Registered Nurse Salary in Mississippi

A registered nurse in Mississippi earns an estimated $83,100 a year ($39.95 an hour). Most workers fall from $56,500 to $120,500, depending on experience and employer.

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Registered Nurse pay in Mississippi

Per yearPer hour
Entry level (estimate)$56,500$27.16
Median (estimate)$83,100$39.95
Experienced (estimate)$120,500$57.93
US national median$93,600$45.00

The Mississippi estimate is 11% below the national median, reflecting local prices and wages.

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Take-home pay

On the median figure a single filer in Mississippi keeps about $63,634 a year after federal tax, FICA and state tax, or $2,447.48 per biweekly paycheck. Try your exact numbers in the Mississippi paycheck calculator.

Frequently asked questions

How much does a registered nurse make in Mississippi?

About $83,100 a year at the median (estimate).

Is this an official figure?

No. It is an estimate based on the national BLS median and a state wage index. Check BLS OEWS tables for official data.

Sources and method

Page last updated November 2026. See our editorial policy and disclaimer.